Other Information: Use only if single-use container is intact. Use before expiration date marked on container. Store at 59-86 degrees F (15-30 degrees C). Retain this carton for future reference. Misc: Triple-action relief. Clinically proven to lubricate, hydrate, and protect natural tears from evaporating. Preservative-free. Sterile. refreshbrand.com. Make your dry eyes feel better with the drops doctors recommend. Refresh Optive Advanced, a preservative-free, go-to drop that works on all three layers of your tear film. This clinically proven triple-action formula: 1. Lubricates for moisturizing dry eye relief. 2. Hydrates the eye surface cells. 3. Protects your natural tears with a lipid-enhanced drop by reducing tear evaporation. Now, you can have long lasting comfort in a visibly light tear. Safe to use as often as needed. No shaking required.